Friday, January 31, 2020

Coronavirus Contains "HIV Insertions", Stoking Fears Over Artificially Created Bioweapon

Over the past few days, the mainstream press has vigorously pushed back against a theory about the origins of the coronavirus that has now infected as many as 70,000+ people in Wuhan alone (depending on whom you believe). The theory is that China obtained the coronavirus via a Canadian research program, and started molding it into a bioweapon at the Institute of Virology in Wuhan. Politifact pointed the finger at Zero Hedge, in particular, though the story was widely shared across independent-leaning media.
The theory is that the virus, which was developed by infectious disease experts to function as a bio-weapon, originated in the Wuhan-based lab of Dr. Peng Zhou, China's preeminent researcher of bat immune systems, specifically in how their immune systems adapt to the presence of viruses like coronavirus and other destructive viruses. Somehow, the virus escaped from the lab, and the Hunan fish market where the virus supposedly originated is merely a ruse.
Now, a respected epidemiologist who recently caught flack for claiming in a twitter threat that the virus appeared to be much more contagious than initially believed is pointing out irregularities in the virus's genome that suggests it might have been genetically engineered for the purposes of a weapon, and not just any weapon but the deadliest one of all.
In "Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag", Indian researchers are baffled by segments of the virus's RNA that have no relation to other coronaviruses like SARS, and instead appear to be closer to HIV. The virus even responds to treatment by HIV medications.
For those pressed for time, here are the key findings from the paper, which first focuses on the unique nature of 2019-nCoV, and then observe four amino acid sequences in the Wuhan Coronavirus which are homologous to amino acid sequences in HIV1:
Our phylogentic tree of full-length coronaviruses suggests that 2019-nCoV is closely related to SARS CoV [Fig1].
In addition, other recent studies have linked the 2019-nCoV to SARS CoV. We therefore compared the spike glycoprotein sequences of the 2019-nCoV to that of the SARS CoV (NCBI Accession number: AY390556.1). On careful examination of the sequence alignment we found that the 2019- nCoV spike glycoprotein contains 4 insertions [Fig.2]. To further investigate if these inserts are present in any other corona virus, we performed a multiple sequence alignment of the spike glycoprotein amino acid sequences of all available coronaviruses (n=55) [refer Table S.File1] in NCBI refseq (ncbi.nlm.nih.gov) this includes one sequence of 2019-nCoV[Fig.S1]. We found that these 4 insertions [inserts 1, 2, 3 and 4] are unique to 2019-nCoV and are not present in other coronaviruses analyzed. Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses . Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses (Zhou et al., 2020).
We then translated the aligned genome and found that these inserts are present in all Wuhan 2019-nCoV viruses except the 2019-nCoV virus of Bat as a host [Fig.S4]. Intrigued by the 4 highly conserved inserts unique to 2019-nCoV we wanted to understand their origin. For this purpose, we used the 2019-nCoV local alignment with each insert as query against all virus genomes and considered hits with 100% sequence coverage. Surprisingly, each of the four inserts aligned with short segments of the Human immunodeficiency Virus-1 (HIV-1) proteins. The amino acid positions of the inserts in 2019-nCoV and the corresponding residues in HIV-1 gp120 and HIV-1 Gag are shown in Table 1.
The first 3 inserts (insert 1,2 and 3) aligned to short segments of amino acid residues in HIV-1 gp120. The insert 4 aligned to HIV-1 Gag. The insert 1 (6 amino acid residues) and insert 2 (6 amino acid residues) in the spike glycoprotein of 2019-nCoV are 100% identical to the residues mapped to HIV-1 gp120. The insert 3 (12 amino acid residues) in 2019- nCoV maps to HIV-1 gp120 with gaps [see Table 1]. The insert 4 (8 amino acid residues) maps to HIV-1 Gag with gaps.
Why do the authors think the virus may be man-made? Because when looking at the above insertions which are not present in any of the closest coronavirus families, "it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time." Instead, they can be found in cell identification and membrane binding proteins located in the HIV genome.
Since the S protein of 2019-nCoV shares closest ancestry with SARS GZ02, the sequence coding for spike proteins of these two viruses were compared using MultiAlin software. We found four new insertions in the protein of 2019-nCoV- “GTNGTKR” (IS1), “HKNNKS” (IS2), “GDSSSG” (IS3) and “QTNSPRRA” (IS4) (Figure 2). To our surprise, these sequence insertions were not only absent in S protein of SARS but were also not observed in any other member of the Coronaviridae family (Supplementary figure). This is startling as it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time.
The insertions were observed to be present in all the genomic sequences of 2019-nCoV virus available from the recent clinical isolates. To know the source of these insertions in 2019-nCoV a local alignment was done with BLASTp using these insertions as query with all virus genome. Unexpectedly, all the insertions got aligned with Human immunodeficiency Virus-1 (HIV-1). Further analysis revealed that aligned sequences of HIV-1 with 2019-nCoV were derived from surface glycoprotein gp120 (amino acid sequence positions: 404-409, 462-467, 136-150) and from Gag protein (366-384 amino acid) (Table 1). Gag protein of HIV is involved in host membrane binding, packaging of the virus and for the formation of virus-like particles. Gp120 plays crucial role in recognizing the host cell by binding to the primary receptor CD4.This binding induces structural rearrangements in GP120, creating a high affinity binding site for a chemokine co-receptor like CXCR4 and/or CCR5.
And some visuals, which lead the paper authors to conclude that "this structural change might have also increased the range of host cells that 2019-nCoV can infect":
3D modelling of the protein structure displayed that these insertions are present at the binding site of 2019-nCoV. Due to the presence of gp120 motifs in 2019-nCoV spike glycoprotein at its binding domain, we propose that these motif insertions could have provided an enhanced affinity towards host cell receptors. Further, this structural change might have also increased the range of host cells that 2019-nCoV can infect. To the best of our knowledge, the function of these motifs is still not clear in HIV and need to be explored. The exchange of genetic material among the viruses is well known and such critical exchange highlights the risk and the need to investigate the relations between seemingly unrelated virus families.
A good recap of the findings was provided by Dr. Feigl-Ding, who started his explanatory thread by pointing out that the transmission rate outside China has surpassed the rate inside China.
2) Whoa- the rate of increase ***outside of China*** is steeper than inside of China or Wuhan! Figure 1A. From: @TheLancet “Nowcasting and forecasting the potential domestic and international spread of 2019-nCoV http://bit.ly/2GF6gZP ”)
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2) Whoa- the rate of increase ***outside of China*** is steeper than inside of China or Wuhan! Figure 1A. From: @TheLancet “Nowcasting and forecasting the potential domestic and international spread of 2019-nCoV http://bit.ly/2GF6gZP ”)
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3) “An estimated 75815 individuals have been infected in Wuhan” —> this is substantially higher than current reports or ~10k reports by China 🇨🇳 media. (75k estimate from above Lancet article)
144 people are talking about this
4) ...”On the present trajectory, 2019-nCoV could be about to become a global epidemic in the absence of mitigation...substantial, even draconian measures that limit population mobility should be seriously and immediately considered in affected areas...” 🤢
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But the 'smoking gun' in this case are pieces of the virus's genetic code that Indian researchers, led by Prashant Pradhan at the Indian Institute of Technology, found may have been 'embedded' from HIV, which belongs to an entirely different family of viruses.
16. UPDATE ON 🦠 GENOME 🧬: a very intriguing new paper investigating the aforementioned mystery middle segment w/ “S” spike protein: likely origin from HIV. “Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag” from https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1 
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17. ...WHOA- the authors said the finding was “Unexpectedly” related to genes from HIV virus. Notably there were 4 gene insertions (see figure in above post #16). And so, which HIV gene proteins were found in the new ? Gag protein and Gp120- key HIV proteins...
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18. Notably, in 🦠S 🧬, authors say for HIV🧬insertions: “Gag protein of HIV is involved in host membrane binding, packaging of the virus and for the formation of virus-like particles. Gp120 plays crucial role in recognizing the host cell by binding to the primary receptor CD4”
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19. Again, these are new express published findings and not peer reviewed yet. Let’s not draw conclusions yet. But evidence suggest that 2 different HIV genes 🧬 are present in the S gene region (that didn’t map to any other coronavirus, according to other studies).
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20. Further the authors add that “This indicates that these insertions have been preferably acquired by the 2019-nCoV, providing it with additional survival and infectivity advantage. Delving deeper we found that these insertions were similar to HIV-1.” 🤔
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21. Paper piles on: “these 🧬insertions are present at binding site of 2019-nCoV. Due to presence of gp120 motifs in 2019-nCoV spike glycoprotein at its binding domain, we propose that these motif insertions could have provided an enhanced affinity towards host cell receptors.”🤒
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22. The authors dunked this final conclusion: “This uncanny similarity of novel inserts in the 2019- nCoV spike protein to HIV-1 gp120 and Gag is unlikely to be fortuitous”. Wow, they sure just went straight there! 😱 What a bold paper... I don’t know what to say 🤷🏻‍♂️
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The punchline:
10. TO BE CLEAR: I am absolutely not saying it’s bioengineering, nor am I supporting any conspiracy theories with no evidence. I’m simply saying scientists need to do more research + get more data. And finding the origin of the virus is an important research priority. Goodnight😴
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Another doctor chimed in with what he thought was a solid explanation for the virus's irregularities...
Sure. 2019-nCoV is a +ve strand RNA virus that enters human cell and first encodes its RNA-replicase to make -ve stranded RNA that serves a template to make +ve strand RNA that is then translated for daughter nCoV. Drugs Lopinavir and Remdesivir target its protease and replicase.
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...Until he realized something disturbing.
Oh my god. Indian scientists have just found HIV (AIDS) virus-like insertions in the 2019-nCov virus that are not found in any other coronavirus. They hint at the possibility that this Chinese virus was designed ["not fortuitous']. Scary if true. https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1.full.pdf 
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"Scary"... but relax, it's just another ridiculous "conspiracy."

Thursday, January 30, 2020

How Viral Pandemic Benefits The Globalist Agenda

The world today suffers from highly fragile economic and geopolitical conditions.  This is not news to most people in the liberty movement that have been tracking the downward spiral for years, but it is news to a majority of average Americans who rarely venture to get in-depth information on any issue.  The fact of the matter is, even though there are millions of us who are aware of the danger, we are still in a minority.
This creates a serious set of frustrations.  When the common citizen is oblivious to the existence of a threat, trying to explain to them the source of that threat becomes a waste of time.  How can they see the root of the problem if they don't even know the problem is there?
Yes, the world is on the verge of a violent sea-change, but this is not the most important issue.  The most important issue is that this precarious situation is not the product of random chance, simple greed, base human frailty or an "overly complex" system as mainstream experts will predictably claim; it is a deliberately engineered chaos box designed to serve the interests of a select few.
The globalist agenda is complicated in design but simple in its goals:  Order out of chaos.  Create or exploit every crisis to manipulate the public into consenting.  But consent for what?
As Richard N. Gardner, former deputy assistant Secretary of State for International Organizations under Kennedy and Johnson, and a member of the Trilateral Commission, wrote in the April, 1974 issue of the Council on Foreign Relation’s (CFR) journal Foreign Affairs (pg. 558) in an article titled 'The Hard Road To World Order':
"In short, the ‘house of world order’ will have to be built from the bottom up rather than from the top down. It will look like a great ‘booming, buzzing confusion,’ to use William James’ famous description of reality, but an end run around national sovereignty, eroding it piece by piece, will accomplish much more than the old-fashioned frontal assault.”
Global pandemic, whether a natural event or deliberately engineered, actually serves the purposes of the globalist establishment in a number of ways. First and foremost, it is a superb distraction. The general public, overcome with fears of an invisible force of nature that can possibly kill them at any moment, will probably forget all about the much bigger threat to their life, liberty and future – the subsequent collapse of the massive 'Everything Bubble' and the globalist "solution" that a pandemic can trigger.
The coronavirus is only a moderate threat in comparison to economic crisis. That said, I want to confront a few issues concerning the virus itself before we get to the economic question.

Virus Disinformation

I have seen a lot of delusional assumptions and outright disinformation being spread by people in regards to this potential pandemic. First, the notion that it was caused by Chinese citizens “eating bats” or being exposed to a live animal market is rather ridiculous. We've seen NO hard evidence whatsoever that this is true, and I believe the narrative is a cover for the fact that the city of Wuhan where the virus outbreak began is the home of not one but TWO level 4 biohazard labs.
I have a hard time ignoring the strange “coincidence” of the high level biohazard labs in Wuhan in favor of the idea that the virus was launched by chance due to the odd diets of central Chinese people. Given the evidence it appears that the coronavirus was gestated in a lab, not in someone's bat and snake soup.  In 2017, scientists outside of China warned that these labs were not secure and that a virus might escape one of the facilities.
I would use the term “escape” loosely, as there is a possibility that this event was created intentionally. The virus itself has certain hallmarks of being engineered (including its long dormant period without visible symptoms) and the current strain is probably derived from the one the Chinese stole a year ago from a lab in Winnipeg, Canada.
But it gets even weirder.
Only three months ago, John Hopkins, the Bill and Melinda Gates Foundation and the World Economic Forum (a hive of self-professed globalists) ran a "pandemic simulation" called "Event 201" specifically focused on Coronavirus.  Not Ebola, or Swine Flu or even Avian Flu - but CORONAVIRUS.  The simulation features the spread of coronavirus in South America, blamed on animal to human transmission (pigs).  The conclusion of the exercise was that national governments were nowhere near ready, scoring 40 out of 100 on their preparedness scale.  The simulation projected over 65 million deaths worldwide.
Event 201 played out almost exactly as it has been in China today.  Some very disingenuous or perhaps rather stupid people have been arguing that this kind of thing is "normal", claiming that we are "lucky" that the elites have been running simulations in advance in order to "save us" from a coronavirus outbreak.  I assert that Event 201 was not a simulation but a war-game to study the possible outcomes of an event the globalists already knew was coming.  Set aside the fact that before almost every major crisis event and terrorist attack for the past few decades authorities were running simulations for that exact event right before it happened; does anyone really believe that Event 201 is pure coincidence?
Another false assumption that needs to be addressed is the idea that a viral threat will not strike the West, or at least, not the US. This odd bias is one that I don't think most cultures except Americans suffer from; the belief that they are untouchable and that the system will always avert crisis. From the responses I have been seeing lately many Americans are living in a fantasy world.  Even now, the investment world is placing full stock and hope in the prediction that the Federal Reserve will step in to disrupt any economic downturn related to the pandemic.
Even if the Fed intended to intervene, why would anyone be naive enough to believe the central bank can do anything about how a viral outbreak damages the economy?  Central banks can do nothing but create debt, and debt will not beat back the coronavirus.
In terms of delusional optimism on the pandemic itself, the arguments range from “screening of travelers is too comprehensive to allow the virus to spread here” and “as long as the virus destroys China, who cares...?” This is a narrow view of the situation.
The screening process is terrible, and usually involves basic questions which can be evaded with lies.  But beyond that, the virus is already here. It was circulating through China for at least a few weeks before it was ever addressed by government authorities or the CDC. It also is reported to be asymptomatic, which means it remains dormant, yet also contagious, for up to two weeks before symptoms become visible. This is a far worse scenario than the ebola scare in 2014, in that the coronavirus is able to hide effectively. The only thing that can be done to slow the spread is to shut down ALL international travel, which the CDC and the WHO have no intention of doing right now, not that it matters anymore with over 110 suspected cases in the US already.
So, let's be realistic. If the virus is as communicable as the CDC and independent scientists claim, then we will see the effects here in America.

Never Let A Good Crisis Go To Waste...

But what do globalists have to gain directly from a coronavirus pandemic beyond simple chaos that can be exploited?
Interestingly, a representative from Johnson and Johnson, one of the companies that may end up designing a "vaccine" for the Cronavirus, suggested during Event 201 that a "centralized" global economic authority in charge of funding and procuring vaccines for various nations in crisis was an option for solving the pandemic.
Gee, that sounds strangely similar to what globalists have been demanding for many years now, and the pandemic just happens to offer a perfect excuse for the creation of such a one-world financial authority.  They might claim that such a system would be temporary according to the life of the pandemic, but this will be a lie.
In terms of the economic effects, even if the virus were to stay primarily in China, the Chinese economy is, in basic terms, the largest in the world; it is the biggest exporter/importer and it is central to the now interdependent global economy. If China's economy goes down, even for a short time, this will send shockwaves through all other national economies and supply lines.
In May of last year I published an article titled 'Globalists Only Need One More Major Event To Finish Sabotaging The Economy'. To summarize the situation:
The globalist establishment has created the largest financial bubble in modern history through central bank stimulus, inflating a highly unstable artificial rally in markets while also creating new highs in national debt, corporate debt and consumer debt. The economic fundamentals have been sending alarms for the past two years, and the 'Everything Bubble' is showing signs of implosion. It is only a matter of time before the farce collapses by itself. The globalists need scapegoats, but they also need an event or wave of events so distracting that people will not be able to discern what really happened.
The reason why globalists want a collapse is simple - They need crisis in order to manipulate the masses into accepting total centralization, a global monetary system and global governance. They are also rabid believers in eugenics and population reduction. At the very least, a global pandemic is a useful happenstance for them; but the timing of the coronavirus event and their highly accurate "simulation" only three months ago also suggests their potential involvement, as it comes right as the implosion of the Everything Bubble was accelerating.
Consider this: Even if a pandemic does not kill a large number of people, it still disrupts international travel, it disrupts exports and imports, it disrupts consumer behavior and retail sales, and it disrupts domestic trade. If it does kill a large number of people, and if the Chinese government's response is any indication, it could result in global martial law. With many economies including the US economy already in a precarious balancing act of historic debt vs. crashing demand and useless central bank repo market intervention, there is little chance that the system can withstand such a tsunami.
Make no mistake, the crash has already begun, whether the virus hits the US hard or not. The only question is, will this be the trigger event that accelerates the collapse process that is already in motion?
I took my time in publishing this article because I believed it was important to first watch the Chinese, CDC and WHO response to the virus. If they dealt with the situation quickly then there was a chance that it would have only minor influence on the financial system. They did not deal with the situation quickly or decisively. In fact, over 5 million people left the Hubei region of China before active quarantine and treatment procedures began. The situation has spiraled out of control in China and it is clear that the government is now lying through its teeth about the number of sick and dead.
I would not be surprised if we discover in the next two weeks that the death tally is in the thousands, and the sickness rate is actually in the hundreds of thousands. The fact that China has now quarantined over 50 million people in 16 cities suggests the danger is much higher than they have admitted.  If this is the case, then at the very least, the Chinese economy is about to take a massive hit. If the virus doesn't spread, the economic damage will.

Pandemic Smokescreen, Economic Collapse And "Climate Change"

Look at it this way – The US and China are still currently in the middle of a trade war. The Phase 1 deal was always a joke, because it demands that China quadruple its purchases from the US within the next 1-2 years. This was never going to happen, but the false hope (along with corporate stock buybacks) lifted global stocks out of reversal. Now, there is no chance that China will meet the requirements of the Phase 1 deal and that will soon become evident, as China's economy will grind down under the weight of the pandemic.
If Trump continues tariffs against a nation in the state of a viral emergency he will look like a monster (which I believe is his job as a globalist puppet pretending to be a conservative nationalist). In the meantime, global trade becomes muddled and the last structural supports of the system snap in half.
With global supply lines frozen and travel eventually restricted, trade will stall.  There is no way around this.  This is not just about China, it is about all nations.  And, ultimately, this is not even about the coronavirus, it is about the financial time bomb that the globalist establishment created.  It is about our economic interdependency and the house of cards we have become.  In the wake of calamity, the globalists will call for even MORE interdependency.  They will claim tragedy struck because we were not "centralized enough".
Another advantage of the viral crisis is that the establishment will undoubtedly blame the "climate change" and "global warming" hoax for its impetus.  Even though there is absolutely no concrete evidence linking human carbon emissions to climate change or viral outbreaks, given enough public fear globalists will attempt to link the three things together as if it is a proven fact.  Not only will they have a rationale for an economic collapse THEY created, but they can also present a virus engineered by humans in a lab as an "act of nature", and use it as a rationale for implementing carbon controls
In the next issue of my Wild Bunch Dispatch Newsletter I will be outlining solutions and preparedness options for surviving a pandemic scenario; all is not lost if this event does accelerate as the globalists predicted in their Event 201 model.  It is still hard to say with certainty, but this appears to be the “black swan” that the globalists were waiting for (or planning) all along.  Remaining vigilant in terms of the pandemic is recommended, but do not forget about the economic disaster that will inevitably follow as the coronavirus continues to spread.